Spondylolisthesis

Spondylolisthesis is a condition of spinal instability, in which one vertebra slips forward over the vertebra below.

Isthmic Spondylolisthesis

Isthmic spondylolisthesis, the most common form of this condition, is caused by a bony defect (or fracture) in an area of the pars interarticularis, an area located in the roof (laminae) of the vertebral structure. This bony defect occurs in approximately 4% of the population, and results from a genetic failure of bone formation. The condition most commonly affects the fourth and fifth lumbar vertebrae (L4 and L5) and the first sacral vertebra (S1). It is interesting to note that the condition is not always painful.

Symptoms

Symptoms may include the following:


  • Low back, thigh, and/or leg pain that radiates into the buttocks
  • Muscle spasms
  • Leg pain or weakness
  • Tight hamstring muscles
  • Irregular gait

Some people are symptom free and only discover the disorder when seeing a doctor for another health problem. In severe cases, the condition may cause swayback and a protruding abdomen, a shortened torso, and a waddling gait.

Causes

Isthmic spondylolisthesis can be the result of a genetic failure of bone formation in the spinal vertebrae. Usually physical stresses to the spine then break down the weak or insufficiently formed vertebral components. Repeated heavy lifting, stooping, or twisting can cause small fractures to occur in the vertebral structure and lead to the slippage of one vertebra over another. Weightlifters, football players, and gymnasts often suffer from this disorder due to the considerable stress placed on their spines.

Diagnosis

To make an accurate diagnosis, physicians generally will conduct a careful and rigorous diagnostic process, including:

  • Medical history. We will talk to you about your symptoms, how severe they are, and what treatments you have already tried.
  • Physical examination. You will be carefully examined by one of our spine specialists for limitations of movement, problems with balance, and pain. During this exam, we will also look for loss of reflexes in the extremities, muscle weakness, loss of sensation or other signs of neurological damage.
  • Diagnostic tests. Generally, we start with plain x-rays, which allow us to rule out other problems such as tumors and infections. We may also use a CT scan or MRI to confirm the diagnosis. In some patients we may need a myelogram. This is a test that involves the use of a liquid dye that is injected into the spinal column to show the degree of nerve compression and slippage between involved vertebrae.

Treatment

There are several methods used to "grade" the degree of slippage ranging from mild to most severe. Your surgeon will discuss with you the extent of your spondylolisthesis and how the severity indicates the type of treatment that is needed.

In general, physicians use the Meyerding Grading System for classifying slips. This is a relatively easy to understand system. Slips are graded on the basis of the percentage that one vertebral body has slipped forward over the vertebral body below. Thus a Grade I slip indicates that 1-24% of the vertebral body has slipped forward over the body below. Grade II indicates a 25-49% slip. Grade III indicates a 50-74% slip and Grade IV indicates a 75%-99% slip. If the body completely slips off the body below it is classified as a Grade V slip, known as spondyloptosis.

Your physician will consider the degree of slip, and such factors as intractable pain and neurological symptoms, when deciding on the most suitable treatment. As a general guideline, the more severe slips (especially Grades III and above) are most likely to require surgical intervention.

For most cases of isthmic spondylolisthesis (especially Grades I and II), treatment consists of temporary bed rest, restriction of the activities that caused the onset of symptoms, pain/ anti-inflammatory medications, steroid-anesthetic injections, physical therapy and/or spinal bracing.
Surgery is rarely needed unless the case is severe (usually Grade III or above), neurological damage has occurred, the pain is disabling, or all non-operative treatment options have failed.

The most common surgical procedure used to treat spondylolisthesis is called a laminectomy and fusion. In this procedure, the spinal canal is widened by removing or trimming the laminae (roof) of the vertebrae. This is done to create more space for the nerves and relieve pressure on the spinal cord. The surgeon may also need to remove all or part of the vertebral disc (discectomy) and then also fuse vertebrae together. If fusion is done, various devices (like screws or interbody cages) may be implanted to enhance fusion and to support the unstable spine.

Prevention

While it may not be possible to prevent all spine problems, there are things you can do to help keep your spine healthy. The most important prevention method is to avoid or limit those work or recreational activities that cause considerable stress to your spine.

We can work closely with you in establishing healthy lifestyle habits that can help keep your back healthy. For example, losing weight, starting a regular exercise regimen, not smoking, and learning proper body mechanics can all help reduce the risk of further back problems.

Degenerative Spondylolisthesis

Degenerative spondylolisthesis, usually occurs in the lumbar spine, especially at L4-L5. It is the result of degenerative changes in the vertebral structure that cause the joints between the vertebrae to slip forward. This type of spondylolisthesis is most common among older female patients, usually those over the age of 60.

Symptoms

Symptoms may include the following:

  • Low back, thigh, and/or leg pain that radiates into the buttocks and/or down the legs
  • Muscle spasms
  • Leg weakness
  • Tight hamstring muscles
  • Irregular gait or limp

Some people with spondylolisthesis are symptom free and only discover the disorder when seeing a doctor for another health problem. However, the forward slip of the vertebral body in severe cases of degenerative spondylolisthesis often leads to spinal stenosis, nerve compression, pain and neurological injury.

Causes

Degenerative spondylolisthesis is usually the result of age and "wear and tear" on the spine that breaks down vertebral components. It is different from isthmic spondylolisthesis in that there is no bone defect. Spinal stenosis tends to occur in the early stages of degenerative spondylolisthesis.

Diagnosis

Correct diagnosis is obviously essential. We utilize the latest diagnostic technologies, combined with examinations by expert physicians, to ensure that the diagnosis is accurate. Diagnostic tools include:

  • Medical history. We will talk to you about your symptoms, their severity, and the treatments you have already tried.
  • Physical examination. You will be carefully examined by one of our spine specialists for limitations of movement, problems with balance, pain, loss of reflexes in the extremities, muscle weakness, loss of sensation or other signs of neurological damage.
  • Diagnostic tests. Generally, we start with x-rays, which allow us to rule out other problems such as tumors and infections. We may also use a CT scan or MRI to confirm the diagnosis. In some patients we may need a myelogram. This is a test that involves the use of a liquid dye that is injected into the spinal column to show the degree of nerve compression and slippage between involved vertebrae.

Classification

There are several methods used to "grade" the degree of slippage ranging from mild to most severe. Your surgeon will discuss with you the extent of your spondylolisthesis.

In general, physicians use the Meyerding Grading System for classifying slips. This is a relatively easy to understand system. Slips are graded on the basis of the percentage that one vertebral body has slipped forward over the vertebral body below. Thus a Grade I slip indicates that 1-24% of the vertebral body has slipped forward over the body below. Grade II indicates a 25-49% slip. Grade III indicates a 50-74% slip and Grade IV indicates a 75%-99% slip. If the body completely slips off the body below it is classified as a Grade V slip, known as spondyloptosis.

Your physician will consider the degree of slip, and such factors as intractable pain and neurological symptoms, when deciding on the most suitable treatment. Most degenerative spondylolisthesis cases involve Grade I or Grade II. As a general guideline, the more severe slips (especially Grades III and above) are most likely to require surgical intervention.

For most cases of degenerative spondylolisthesis (especially Grades I and II), treatment consists of temporary bed rest, restriction of the activities that caused the onset of symptoms, pain/ anti-inflammatory medications, steroid-anesthetic injections, physical therapy and/or spinal bracing.

Surgery is rarely needed unless the case is severe (usually Grade III or above), neurological damage has occurred, the pain is disabling, or all non-operative treatment options have failed.

Treatment

For most cases of degenerative spondylolisthesis, treatment consists of temporary bed rest, restriction of the activities that caused the onset of symptoms, pain/ anti-inflammatory medications, steroid-anesthetic injections, physical therapy and/or spinal bracing.

Degenerative spondylolisthesis can be progressive – meaning the damage will continue to get worse as time goes on. In addition, degenerative spondylolisthesis can cause stenosis, a narrowing of the spinal canal and spinal cord compression. If the stenosis is severe, and all non-operative treatments have failed, surgery may be necessary.

The most common surgical procedure used to treat spondylolisthesis is called a laminectomy and fusion. In this procedure, the spinal canal is widened by removing or trimming the laminae (roof) of the vertebrae. This is done to create more space for the nerves and relieve pressure on the spinal cord. The surgeon may also need to fuse vertebrae together. If fusion is done, various devices (like screws or interbody cages) may be implanted to enhance fusion and support the unstable spine.

We Can Help

Most people will experience some degenerative changes in their spines as they age. However, severe spondylolisthesis only affects a small percentage of the population. Overall, most degenerative disorders of the spine can be treated successfully using non-surgical methods. We can work closely with you to find a treatment method that is best for you and help you return to an active, and pain-free, lifestyle.

 

 

Spinal Conditions

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